My left leg is about half an inch shorter than my right. Pictures of me as a kid show that my left leg wasn't straight up and down - it looked bashed inward at the knee. Somehow nobody thought of this as a problem. (Then again, our "health care" during my childhood consisted of "don't get sick.")
Nowadays, this means that I lean slightly to the left (even when I'm sitting down, apparently), that touching my left toe is much easier than touching my right toe, and that standing still is nearly impossible - I have to shift around a lot. Too much walking kills my right hip, which in turn kills every other joint in both legs when I try to compensate by walking different, and eventually my lower then upper back. Also, my present exercise routine tends to leave my right hip seriously sore for days.
My current shoes have soles that are an inch and a half tall. I've recently discovered that walking around with only my left shoe on feels really nice to my right hip.